Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712486 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL10686251 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL1938539 | 0.80 | TDP1 (0.40) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL20810981 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL5535005 | 0.74 | HPGD (0.39) | CYP3A4L3MBTL1 | |
| SCHEMBL2353914 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL28659258 | 0.74 | TSHR (0.52) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL28136370 | 0.74 | MCL1 (0.46) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL14553753 | 0.74 | TDP1 (0.50) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL27336138 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |