Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361277 | 0.84 | VCAM1 (0.49) | TDP1ATMTSHRHIF1AALDH1A1 | |
| SCHEMBL7295438 | 0.82 | TSHR (0.42) | TDP1ATMTSHRHIF1AALDH1A1 | |
| SCHEMBL9712485 | 0.80 | ALDH1A1 (0.42) | TDP1TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL30924883 | 0.76 | TDP1 (0.50) | TDP1ATMTSHRHIF1AALDH1A1 | |
| SCHEMBL825499 | 0.76 | TDP1 (0.50) | TDP1ATMTSHRHIF1AALDH1A1 | |
| SCHEMBL11823433 | 0.76 | TSHR (0.40) | TDP1ATMTSHRALDH1A1GPR35 | |
| SCHEMBL698798 | 0.76 | TDP1 (0.47) | TDP1ATMTSHRALDH1A1GPR35 | |
| SCHEMBL18311461 | 0.75 | TDP1 (0.56) | TDP1ATMTSHRHIF1AALDH1A1 | |
| SCHEMBL55225 | 0.73 | GPR35 (0.55) | TDP1TSHRALDH1A1GPR35HPGD | |
| SCHEMBL28259777 | 0.73 | GPR35 (0.55) | TDP1ATMTSHRHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331561-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | Xenome Ltd (AU) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025510-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2010-03-11 | — | — | WO | disclosed |