Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712524 | 0.87 | ALDH1A1 (0.47) | SRD5A2CES2CES1HPGDPTGS2 | |
| SCHEMBL9712334 | 0.86 | SRD5A2 (0.44) | SRD5A2MAPK1CES2CES1HPGD | |
| SCHEMBL8432335 | 0.86 | ALDH1A1 (0.43) | SRD5A2CES2CES1CA1CA2 | |
| SCHEMBL9712500 | 0.79 | SRD5A2 (0.44) | SRD5A2MAPK1CES2CES1HPGD | |
| SCHEMBL1312683 | 0.77 | CES2 (0.44) | CES2CES1HPGDTSHR | |
| SCHEMBL9712397 | 0.76 | SRD5A2 (0.44) | SRD5A2MAPK1CES2CES1HPGD | |
| SCHEMBL7581124 | 0.75 | SRD5A2 (0.47) | SRD5A2MAPK1CES2CES1HPGD | |
| SCHEMBL9712444 | 0.75 | NR4A1 (0.53) | SRD5A2MAPK1CES2CES1HPGD | |
| SCHEMBL9712594 | 0.73 | ALDH1A1 (0.47) | SRD5A2CES2CES1HPGDGSK3B | |
| SCHEMBL9492447 | 0.73 | NPC1 (0.35) | CES2CES1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |