SCHEMBL971256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL973764	0.85	BTK (0.45)	HRH3CHRNA7BTKDPP4ACKR3
	SCHEMBL973986	0.85	SMPD3 (0.41)	SMPD3BTKDPP4NPC1RAB9A
	SCHEMBL973812	0.84	HRH3 (0.38)	SMPD3HRH3CHRNA7BTKDPP4
	SCHEMBL973571	0.83	HRH3 (0.37)	SMPD3HRH3CHRNA7BTKDPP4
	SCHEMBL971906	0.83	SMPD3 (0.41)	SMPD3HRH3BTKDPP4ACKR3
	SCHEMBL974821	0.83	HRH3 (0.38)	SMPD3HRH3CHRNA7BTKDPP4
	SCHEMBL974422	0.83	BTK (0.38)	HRH3CHRNA7BTKDPP4ACKR3
	SCHEMBL972148	0.83	GRM5 (0.39)	HRH3CHRNA7BTKACKR3CA12
	SCHEMBL975872	0.82	CA12 (0.41)	HRH3CHRNA7BTKDPP4ACKR3
	SCHEMBL975864	0.82	BTK (0.38)	SMPD3HRH3CHRNA7BTKACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.