SCHEMBL972148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL973764	0.87	BTK (0.45)	GRM5BTKHRH3ACKR3CHRNA7
	SCHEMBL973571	0.85	HRH3 (0.37)	BTKHRH3ACKR3CA12CA1
	SCHEMBL974422	0.85	BTK (0.38)	BTKHRH3NSD2ACKR3CHRNA7
	SCHEMBL973812	0.84	HRH3 (0.38)	BTKHRH3ACKR3SMN1; SMN2CHRNA7
	SCHEMBL975872	0.84	CA12 (0.41)	BTKHRH3ACKR3CA12CA1
	SCHEMBL974821	0.83	HRH3 (0.38)	BTKHRH3ACKR3CHRNA7
	SCHEMBL971256	0.83	SMPD3 (0.37)	BTKHRH3NSD2ACKR3CA12
	SCHEMBL973568	0.82	CA12 (0.42)	HRH3CA12CA1CA2CA4
	SCHEMBL975864	0.82	BTK (0.38)	GRM5BTKHRH3ACKR3CA12
	SCHEMBL974669	0.82	HRH3 (0.39)	BTKHRH3ACKR3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.