SCHEMBL973812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL974821	0.91	HRH3 (0.38)	HRH3BTKCHRNA7DRD2HTR2A
	SCHEMBL973764	0.91	BTK (0.45)	HRH3BTKCHRNA7DRD2HTR2A
	SCHEMBL974422	0.90	BTK (0.38)	HRH3BTKCYP46A1CHRNA7DRD2
	SCHEMBL974669	0.89	HRH3 (0.39)	HRH3BTKCHRNA7DRD2HTR2A
	SCHEMBL973310	0.89	TRPV1 (0.41)	USP30SMPD3
	SCHEMBL973017	0.87	NAAA (0.46)	HRH3BTKTMPRSS15SMPD3
	SCHEMBL975864	0.85	BTK (0.38)	HRH3BTKCHRNA7DRD2HTR2A
	SCHEMBL973006	0.85	HRH3 (0.37)	HRH3CHRNA7DPP4SMPD3
	SCHEMBL972148	0.84	GRM5 (0.39)	HRH3BTKCHRNA7ACKR3USP30
	SCHEMBL971256	0.84	SMPD3 (0.37)	HRH3BTKCHRNA7DPP4ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.