Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8172603 | 0.87 | NR4A1 (0.40) | NR4A1AKR1C3KMT2ACNR1CNR2 | |
| SCHEMBL7648621 | 0.84 | AKR1C3 (0.66) | NR4A1AKR1C3KMT2ACDC25BATM | |
| SCHEMBL7848544 | 0.83 | HTT (0.47) | NR4A1AKR1C3KMT2ACNR1CNR2 | |
| SCHEMBL6299251 | 0.82 | NR4A1 (0.72) | NR4A1AKR1C3KMT2ACDC25BATM | |
| SCHEMBL9712437 | 0.81 | CNR1 (0.40) | KMT2ACNR1CNR2CYP2C9USP5 | |
| SCHEMBL11858542 | 0.81 | LIG1 (0.65) | NR4A1AKR1C3KMT2ACNR1CNR2 | |
| SCHEMBL7144396 | 0.80 | AKR1C3 (0.70) | NR4A1AKR1C3KMT2ACDC25BATM | |
| SCHEMBL30816995 | 0.79 | MAPT (0.65) | MAPTPOLBALDH1A1 | |
| SCHEMBL10373078 | 0.79 | MAPT (0.65) | MAPTPOLBALDH1A1 | |
| SCHEMBL11529162 | 0.79 | ESRRA (0.56) | NR4A1AKR1C3KMT2ACYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |