Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759830 | 0.85 | CES2 (0.62) | ABCC9ABCC8KCNJ11KCNJ8GAA | |
| SCHEMBL11527434 | 0.84 | ABCC9 (0.45) | ESRRAKAT6AABCC9ABCC8KCNJ11 | |
| SCHEMBL15197127 | 0.82 | KAT6A (0.52) | ESRRAKAT6AGAACES2CES1 | |
| SCHEMBL11524017 | 0.82 | ABCC9 (0.43) | ESRRAKAT6AABCC9ABCC8KCNJ11 | |
| SCHEMBL11757190 | 0.81 | CES2 (0.46) | ESRRAABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7648621 | 0.81 | AKR1C3 (0.66) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL11858542 | 0.81 | LIG1 (0.65) | ESRRAGAAALDH1A1ALOX15MEN1 | |
| SCHEMBL1630752 | 0.80 | AKR1C3 (0.65) | ABCC9ABCC8KCNJ11KCNJ8GAA | |
| SCHEMBL29779621 | 0.80 | NR4A1 (0.65) | ABCC9ABCC8KCNJ11KCNJ8GAA | |
| SCHEMBL4638623 | 0.80 | CES2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145444-A | 4-BUTYL-BENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4124726-A | 2-FLUORO-4'-ALKYLBENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |