Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19574958 | 0.90 | TSHR (0.45) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL4439576 | 0.85 | MMP12 (0.45) | TSHRCYP2C19HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4439569 | 0.85 | MMP12 (0.45) | TSHRCYP2C19HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11769415 | 0.81 | CA1 (0.50) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL4443937 | 0.81 | CA1 (0.50) | TSHRTDP1L3MBTL1CYP2C19CA1 | |
| SCHEMBL4443943 | 0.81 | CA1 (0.50) | TSHRTDP1L3MBTL1CYP2C19CA1 | |
| SCHEMBL3742621 | 0.81 | TSHR (0.52) | TSHRCYP2C19NAAACA1CA2 | |
| SCHEMBL16572207 | 0.81 | TSHR (0.52) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL27440241 | 0.80 | TRPA1 (0.47) | TSHRTDP1L3MBTL1CYP2C19NAAA | |
| SCHEMBL14763820 | 0.80 | TSHR (0.56) | TSHRTDP1L3MBTL1CYP2C19NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |