Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MMP1 | P03956 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622299 | 0.86 | MMP1 (0.68) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL7622295 | 0.86 | MMP1 (0.68) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL27479697 | 0.86 | NPC1 (0.64) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL648951 | 0.84 | NPC1 (0.62) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL26640096 | 0.84 | NPC1 (0.62) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL23306418 | 0.82 | MMP1 (0.68) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL5766105 | 0.82 | HPGD (0.63) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL9360564 | 0.81 | MMP1 (0.71) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL5176479 | 0.81 | MMP1 (0.71) | NPC1RAB9AHPGDALDH1A1MMP1 | |
| SCHEMBL29451127 | 0.81 | HPGD (0.62) | NPC1RAB9AHPGDALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-5081287-A | Pesticidal polyhalo alkenoic acid esters | FMC CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | disclosed |