SCHEMBL648951

SCHEMBL648951

C=CC(=O)Nc1ccccc1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
HPGD P15428 5/20 0.60
MMP1 P03956 4/20 0.60
MMP2 P08253 4/20 0.60
MMP9 P14780 4/20 0.60
ALDH1A1 P00352 3/20 0.60
EGFR P00533 1/20 0.60
TGM2 P21980 2/20 0.55
POLB P06746 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
ALOX12 P18054 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
EPHX1 P07099 1/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL27744877 0.95 MMP1 (0.59) NPC1RAB9AHPGDMMP1MMP2
SCHEMBL613090 0.86 TGM2 (0.65) ALDH1A1EGFRTGM2SMN1; SMN2MAPT
SCHEMBL31228347 0.86 TGM2 (0.65) ALDH1A1EGFRTGM2SMN1; SMN2MAPT
SCHEMBL17931668 0.85 NPC1 (0.51) NPC1RAB9AHPGDALDH1A1TGM2
SCHEMBL31162452 0.85 NPC1 (0.51) NPC1RAB9AHPGDALDH1A1TGM2
SCHEMBL9712813 0.84 NPC1 (0.67) NPC1RAB9AHPGDMMP1MMP2
SCHEMBL11508899 0.84 FGFR4 (0.50) MMP1MMP2MMP9EGFRTGM2
SCHEMBL2761954 0.82 TGM2 (0.62) HPGDMMP1MMP2MMP9ALDH1A1
SCHEMBL27479697 0.82 NPC1 (0.64) NPC1RAB9AHPGDMMP1MMP2
SCHEMBL21287459 0.82 TGM2 (0.46) NPC1RAB9AMMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119907921-A Engineered particles as red blood cell mimics for hematology and compositions containing the same 弹弓生物科学公司 2025-04-29 CN claimed
CN-118955381-A Pyrazole compound as well as preparation method and application thereof 赣南师范大学 2024-11-15 CN claimed
CN-114923837-A Hydrogel particles with tunable optical properties and methods of using the same 弹弓生物科学公司 2022-08-19 CN claimed
CN-107615062-B Hydrogel particles with tunable optical properties and methods of using the same 弹弓生物科学公司 2022-03-18 CN claimed
CN-109422673-A A method of synthesis indole ketone compound containing iodine 浙江工业大学 2019-03-05 CN claimed
CN-107151224-A A kind of synthetic method of the alkyl-indol ketone derivatives of 3 methyl 3 江苏理工学院 2017-09-12 CN claimed
CN-105693719-B A kind of synthetic method of 3,3 spiro indole ketone compounds 南阳师范学院 2017-06-16 CN claimed
CN-102006873-B Methods of modulating the activity of the mc5 receptor and treatment of conditions related to this receptor MIMETICA PTY LTD 2013-09-18 CN claimed
CN-102006873-A Methods of modulating the activity of the mc5 receptor and treatment of conditions related to this receptor MIMETICA PTY LTD 2011-04-06 CN claimed
CN-102007105-A 3-aminoalkyl-1, 4-diaza-2-one melanocortin-5 receptor antagonists MIMETICA PTY LTD 2011-04-06 CN claimed
US-7504446-B2 Aqueous inks containing colored polymers XEROX CORPORATION (US) 2009-03-17 US claimed
US-20060074142-A1 Aqueous inks containing colored polymers XEROX CORPORATION 2006-04-06 US claimed
EP-0262796-B1 Resin compositons and their manufacturing method TORAY INDUSTRIES (JP) 1993-11-03 EP claimed
EP-0262796-A2 Resin compositons and their manufacturing method TORAY INDUSTRIES, INC. (JP) 1988-04-06 EP claimed
CN-116162039-B Synthesis method of visible light mediated butanediamide compound 河南师范大学 2025-02-07 CN disclosed
CN-118955381-A Pyrazole compound as well as preparation method and application thereof 赣南师范大学 2024-11-15 CN disclosed
CN-118355112-A Hydrogel particles as feeder cells and as synthetic antigen presenting cells 弹弓生物科学公司 2024-07-16 CN disclosed
US-4121032-A Process for preparing alternating copolymer of conjugated vinyl compound and olefinic unsaturated compound with oxygen and boron compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-17 US disclosed
US-3989882-A Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US disclosed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US disclosed