Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712779 | 0.87 | TP53 (0.43) | TP53TSHRSMN1; SMN2ABL1TRPV1 | |
| SCHEMBL9712903 | 0.74 | TSHR (0.35) | MCHR1TP53TSHRGRM5SMN1; SMN2 | |
| SCHEMBL9713015 | 0.67 | ALDH1A1 (0.48) | TP53TSHRSMN1; SMN2ABL1NPC1 | |
| SCHEMBL9713361 | 0.66 | ALDH1A1 (0.39) | TP53TSHRSMN1; SMN2ABL1NPC1 | |
| SCHEMBL9712822 | 0.64 | ALDH1A1 (0.43) | TP53TSHRSMN1; SMN2ABL1NPC1 | |
| SCHEMBL9712935 | 0.63 | TSHR (0.49) | TP53TSHRSMN1; SMN2TRPV1NPC1 | |
| SCHEMBL9713333 | 0.63 | ALDH1A1 (0.47) | TSHRSMN1; SMN2ABL1NPC1RAB9A | |
| SCHEMBL9713207 | 0.61 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2ABL1MEN1KMT2A | |
| SCHEMBL9712698 | 0.60 | BRAF (0.41) | TP53SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9713311 | 0.59 | CA9 (0.50) | TP53TSHRSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |