Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713792 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2ABL1SRCALDH1A1KDM4E | |
| SCHEMBL9713078 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2ABL1SRCALDH1A1KDM4E | |
| SCHEMBL9713049 | 0.71 | ALDH1A1 (0.36) | SMN1; SMN2ABL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9713015 | 0.71 | ALDH1A1 (0.48) | SMN1; SMN2ABL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9712698 | 0.71 | BRAF (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9712877 | 0.69 | KDM4E (0.33) | SMN1; SMN2ABL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9713194 | 0.68 | ALDH1A1 (0.48) | SMN1; SMN2ABL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9712694 | 0.68 | BRAF (0.39) | SMN1; SMN2 | |
| SCHEMBL9712943 | 0.66 | CYP1A2 (0.41) | TSHRHTTGAA | |
| SCHEMBL9713900 | 0.66 | MAPK14 (0.50) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |