Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713083 | 0.87 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10ABL1RIN1 | |
| SCHEMBL9712792 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10PPARAABL1 | |
| SCHEMBL9713046 | 0.72 | CYP1A2 (0.41) | ALDH1A1PPARAPLK1ALOX5PTGS2 | |
| SCHEMBL9712776 | 0.72 | CYP1A2 (0.36) | PPARAPLK1ALOX5PTGS2TSHR | |
| SCHEMBL9713027 | 0.71 | PLK1 (0.36) | KDM4EPPARAPLK1TSHRTP53 | |
| SCHEMBL9713194 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10ABL1RIN1 | |
| SCHEMBL9713207 | 0.69 | SMN1; SMN2 (0.34) | KDM4EALDH1A1HSD17B10ABL1RIN1 | |
| SCHEMBL9712900 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10ABL1RIN1 | |
| SCHEMBL9712823 | 0.68 | SMN1; SMN2 (0.33) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL9713420 | 0.67 | CYP1A2 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |