Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604837 | 0.78 | L3MBTL1 (0.44) | TDP1L3MBTL1 | |
| SCHEMBL15121919 | 0.77 | FFAR1 (0.57) | TDP1L3MBTL1S1PR1 | |
| Hydrochloric Acid SCHEMBL9713561 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL4657637 | 0.77 | FFAR1 (0.62) | S1PR1F2ELANE | |
| SCHEMBL13432593 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1MAPT | |
| SCHEMBL16715459 | 0.72 | MAPT (0.48) | KDM4EALDH1A1MAPTL3MBTL1S1PR1 | |
| SCHEMBL9076062 | 0.71 | FFAR1 (0.52) | KDM4EALDH1A1TDP1S1PR1 | |
| SCHEMBL13443150 | 0.70 | CHRM2 (0.52) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL19612474 | 0.70 | CYP11B1 (0.56) | MAOAMAOB | |
| SCHEMBL13052431 | 0.70 | HSD17B10 (0.51) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |