SCHEMBL9713237

SCHEMBL9713237

CCC(C)(CC)c1cc(N)[nH]n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234891 0.79 HPGD (0.44) HPGDTSHR
SCHEMBL13464275 0.78 HPGD (0.33) HPGDTSHR
SCHEMBL15831730 0.75 CDK8 (0.33) HPGDTSHR
SCHEMBL2797934 0.74 PRKAB2 (0.32) HPGDTSHR
SCHEMBL20730381 0.74 HPGD (0.32) HPGDTSHR
SCHEMBL10291287 0.73 GRIN2D (0.35) HPGDTSHR
SCHEMBL9713171 0.73
SCHEMBL16445658 0.72 HPGD (0.30) HPGDTSHR
SCHEMBL237855 0.70 CA2 (0.40)
SCHEMBL24565682 0.69 CNR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086184-A Herbicides DOWELANCO (US) 1992-02-04 US disclosed
US-4943634-A HERBICIDES ELI LILLY AND COMPANY (US) 1990-07-24 US disclosed
US-4801718-A HERBICIDES ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed
US-4636243-A HERBICIDES ISOXAZOLES ELI LILLY AND COMPANY (US) 1987-01-13 US disclosed
US-4515625-A HERBICIDES ELI LILLY AND COMPANY (US) 1985-05-07 US disclosed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed
US-4416683-A HERBICIDES ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed