Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713710 | 0.97 | ACACB (0.47) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL9713352 | 0.96 | ACACB (0.46) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL9712998 | 0.96 | ACACB (0.46) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL10515393 | 0.96 | ACACB (0.46) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL9713536 | 0.96 | ACACB (0.46) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL9713435 | 0.93 | ACACB (0.49) | ACACBFFAR1FFAR4CETPMCHR1 | |
| SCHEMBL9712775 | 0.90 | ACACB (0.50) | ACACBMAPTL3MBTL1FFAR1FFAR4 | |
| SCHEMBL9713202 | 0.88 | ACACB (0.46) | ACACBFFAR1FFAR4MCHR1 | |
| SCHEMBL9712834 | 0.87 | ACACB (0.48) | ACACBMCHR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9713143 | 0.86 | MCHR1 (0.37) | ACACBMAPTL3MBTL1RAB9ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164114-A | LIQUID CRYSTAL | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1992-11-17 | — | — | US | disclosed |
| EP-0306521-B1 | ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0306521-A1 | ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
| WO-1988007516-A1 | ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |