Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CASP6 | P55212 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901433 | 0.83 | AURKA (0.53) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL229199 | 0.83 | AURKA (0.53) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL26983155 | 0.81 | AURKA (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL8379561 | 0.81 | AURKA (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL10539390 | 0.80 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL156092 | 0.80 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL29706553 | 0.80 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL445795 | 0.79 | AURKA (0.60) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL10539372 | 0.79 | AURKA (0.60) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL11568447 | 0.78 | ALDH1A1 (0.57) | AURKAAURKBHSD17B10ALDH1A1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305021-B1 | REACTIVE MONOAZO DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1992-01-29 | — | — | EP | disclosed |
| EP-0177445-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1986-04-09 | — | — | EP | disclosed |