Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.48 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.48 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901433 | 1.00 | AURKA (0.53) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL26983155 | 0.98 | AURKA (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL8379561 | 0.98 | AURKA (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL11568447 | 0.88 | ALDH1A1 (0.57) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL156092 | 0.87 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL10539390 | 0.87 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL29706553 | 0.87 | AURKA (0.62) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL29642783 | 0.85 | TIMP3 (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL20577653 | 0.85 | TIMP3 (0.51) | AURKAAURKBHSD17B10ALDH1A1CASP6 | |
| SCHEMBL445795 | 0.85 | AURKA (0.60) | AURKAAURKBHSD17B10ALDH1A1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118045574-A | S-triazine modified straw-based dye adsorbent and preparation method and application thereof | 青岛理工大学 | 2024-05-17 | — | — | CN | claimed |
| US-8633250-B2 | Cell repair and regeneration by suramin and related polysulfonated napthylureas | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-01-21 | — | — | US | claimed |
| US-20110034559-A1 | Cell Repair And Regeneration By Suramin And Related Polysulfonated Naphthylureas | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2011-02-10 | — | — | US | claimed |
| US-20070203234-A1 | CELL REPAIR AND REGENERATION BY SURAMIN AND RELATED POLYSULFONATED NAPTHYLUREAS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2007-08-30 | — | — | US | claimed |
| EP-0477195-A1 | SURAMIN TYPE COMPOUNDS AND ANGIOSTATIC STEROIDS TO INHIBIT ANGIOGENESIS | THE UPJOHN COMPANY (US) | 1992-04-01 | — | — | EP | claimed |
| US-5021557-A | Copper-containing formazan dye, colorfast blue shades on cellulose | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | claimed |
| WO-1990015816-A1 | SURAMIN TYPE COMPOUNDS AND ANGIOSTATIC STEROIDS TO INHIBIT ANGIOGENESIS | THE UPJOHN COMPANY (US) | 1990-12-27 | — | — | WO | claimed |
| EP-0333656-A1 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | claimed |
| US-4609503-A | HYDROXYLATION | BAYER AKTIENGESSELSCHAFT (DE) | 1986-09-02 | — | — | US | claimed |
| EP-0064693-B1 | PROCESS FOR THE PRODUCTION OF 1-BENZOYLAMINO-8-HYDROXYNAPHTHALENE-4,6-DISULPHONIC ACID (BENZOYL K-ACID) | BAYER AG (DE) | 1985-04-10 | — | — | EP | claimed |
| US-4426333-A | Process for the preparation of 1-benzoylamino-8-hydroxynaphthalene-4,6-disulphonic acid (benzoyl-K acid) | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | claimed |
| US-4376737-A | Process for the production of naphthylaminehydroxysulphonic acids | CIBA-GEIGY AG (CH) | 1983-03-15 | — | — | US | claimed |
| EP-0064693-A1 | Process for the production of 1-benzoylamino-8-hydroxynaphthalene-4,6-disulphonic acid (benzoyl K-acid) | BAYER AG (DE) | 1982-11-17 | — | — | EP | claimed |
| EP-0009743-B1 | PROCESS FOR THE PREPARATION OF 1-AMINO-8-HYDROXY-NAPHTHALENE-4,6-DISULPHONIC ACID (K ACID) | BAYER AG (DE) | 1982-01-27 | — | — | EP | claimed |
| EP-0009743-A1 | Process for the preparation of 1-amino-8-hydroxy-naphthalene-4,6-disulphonic acid (K acid) | BAYER AG (DE) | 1980-04-16 | — | — | EP | claimed |
| EP-4574815-A1 | PROCESS FOR THE SEPARATION OF AROMATIC SULPHONIC ACIDS AND SALTS FROM AQUEOUS PHASES | Saltigo GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| US-12331096-B2 | Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto | George Mason Research Foundation, Inc. (US) | 2025-06-17 | — | — | US | disclosed |
| US-4061627-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4054559-A | Reactive disazo monohalogenotriazine dyestuffs | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-10-18 | — | — | US | disclosed |
| US-3957728-A | MODIFIED WITH S-TRIAZINES; ABSORBENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203234-A1 | CELL REPAIR AND REGENERATION BY SURAMIN AND RELATED POLYSULFONATED NAPTHYLUREAS | TST, NES, PTDSS1 | AURKA 4785/4885AURKB 4773/4885HSD17B10 2881/4885 |
| US-12331096-B2 | Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto | SNRPE, SSBP1, RPA1 | AURKA 3644/4885AURKB 1915/4885HSD17B10 3628/4885 |
| US-20110034559-A1 | Cell Repair And Regeneration By Suramin And Related Polysulfonated Naphthylureas | NES, NANS, NME4 | AURKA 4867/4885AURKB 4749/4885HSD17B10 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.