Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628518 | 1.00 | CYP19A1 (0.47) | CYP19A1ALKBH3PPARGESR1ESR2 | |
| SCHEMBL30004012 | 0.85 | ALKBH3 (0.53) | CYP19A1ALKBH3ESR1ESR2ALDH1A1 | |
| SCHEMBL9656985 | 0.85 | ALKBH3 (0.53) | CYP19A1ALKBH3ESR1ESR2ALDH1A1 | |
| SCHEMBL9629320 | 0.83 | PPARG (0.48) | CYP19A1PPARGALDH1A1MEN1MAPT | |
| SCHEMBL23271934 | 0.78 | TDP2 (0.55) | CYP19A1ALKBH3ESR1ESR2ALDH1A1 | |
| SCHEMBL30003100 | 0.78 | TDP2 (0.55) | CYP19A1ALKBH3ESR1ESR2ALDH1A1 | |
| SCHEMBL7451901 | 0.77 | CA1 (0.57) | CYP19A1ESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL2252533 | 0.77 | CA1 (0.57) | CYP19A1ESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL9713912 | 0.77 | PPARG (0.49) | CYP19A1PPARGALDH1A1MEN1MAPT | |
| SCHEMBL16745457 | 0.76 | ALKBH3 (0.52) | ALKBH3PPARGESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |