Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.67 |
| ▸ | CTSS | P25774 | 4/20 | 0.67 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848448 | 1.00 | CTSL (0.67) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL9383939 | 1.00 | CTSL (0.67) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL10572092 | 1.00 | CTSL (0.67) | CTSLCTSSCTSKCTSBATM | |
| Water SCHEMBL10848660 | 0.99 | CTSS (0.69) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL10840026 | 0.95 | CTSL (0.61) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL10840325 | 0.95 | CTSL (0.61) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL10840321 | 0.95 | CTSL (0.61) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL7331078 | 0.90 | ECE1 (0.64) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL13973861 | 0.90 | ECE1 (0.64) | CTSLCTSSCTSKCTSBATM | |
| SCHEMBL7305552 | 0.90 | ECE1 (0.64) | CTSLCTSSCTSKCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253190-B1 | PARTIALLY RETRO-INVERTED TUFTSIN ANALOGUES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ENIRICERCHE S.p.A. (IT) | 1992-12-30 | — | — | EP | disclosed |
| US-4816560-A | STORAGE STABILITY | ENIRICERCHE S.P.A. (IT) | 1989-03-28 | — | — | US | disclosed |
| EP-0253190-A2 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them | ENIRICERCHE S.p.A. (IT) | 1988-01-20 | — | — | EP | disclosed |