Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642964 | 0.84 | ABCB11 (0.38) | ALOX5HTTMAPK1ALDH1A1KDM4E | |
| SCHEMBL9713799 | 0.84 | ALDH1A1 (0.36) | ALOX5HTTMAPK1POLBALDH1A1 | |
| SCHEMBL9713909 | 0.84 | HTT (0.40) | ALOX5HTTMAPK1POLBALDH1A1 | |
| SCHEMBL9641723 | 0.82 | PDE4A (0.39) | ALOX5HTTMAPK1ALDH1A1KDM4E | |
| SCHEMBL9642596 | 0.80 | PDE4A (0.39) | ALOX5HTTMAPK1ALDH1A1KDM4E | |
| SCHEMBL9713621 | 0.80 | HTT (0.39) | HTTMAPK1POLBALDH1A1KDM4E | |
| SCHEMBL9642181 | 0.78 | PDE4A (0.34) | ALOX5MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL9642226 | 0.78 | PDE4A (0.34) | ALOX5MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL9642068 | 0.78 | TSHR (0.34) | ALOX5MAPK1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9642389 | 0.78 | TSHR (0.34) | ALOX5MAPK1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |