Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 15/20 | 0.37 |
| ▸ | MPEG1 | Q2M385 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713615 | 0.99 | PTPN1 (0.43) | PTPN1CDC25BPTPRCALOX5 | |
| SCHEMBL9713391 | 0.95 | ELANE (0.41) | PTPN1CDC25BPTPRC | |
| SCHEMBL9713582 | 0.91 | CDC25B (0.41) | PTPN1CDC25BPTPRC | |
| SCHEMBL9713528 | 0.85 | CDC25B (0.54) | PTPN1CDC25BPTPRC | |
| SCHEMBL9642991 | 0.83 | PTPN1 (0.49) | PTPN1CDC25B | |
| SCHEMBL9713507 | 0.83 | PTPN1 (0.41) | PTPN1CDC25BPTPRC | |
| SCHEMBL9642416 | 0.82 | PTPN1 (0.50) | PTPN1CDC25B | |
| SCHEMBL9713515 | 0.81 | CDC25B (0.36) | PTPN1CDC25BPTPRC | |
| SCHEMBL9713908 | 0.80 | CDC25B (0.56) | PTPN1CDC25BPTPRC | |
| SCHEMBL11247136 | 0.80 | CDC25B (0.56) | PTPN1CDC25BPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |