Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713486 | 0.99 | PTPN1 (0.42) | PTPN1CDC25BPTPRCALOX5 | |
| SCHEMBL9713391 | 0.96 | ELANE (0.41) | PTPN1CDC25BPTPRCELANEGAPDH | |
| SCHEMBL9713582 | 0.92 | CDC25B (0.41) | PTPN1CDC25BPTPRCELANEGAPDH | |
| SCHEMBL9713528 | 0.86 | CDC25B (0.54) | PTPN1CDC25BPTPRCGAPDHTDP1 | |
| SCHEMBL9713507 | 0.84 | PTPN1 (0.41) | PTPN1CDC25BPTPRCGAPDHIDO1 | |
| SCHEMBL9642416 | 0.83 | PTPN1 (0.50) | PTPN1CDC25BELANETDP1 | |
| SCHEMBL9713515 | 0.82 | CDC25B (0.36) | PTPN1CDC25BPTPRCELANEGAPDH | |
| SCHEMBL9642991 | 0.82 | PTPN1 (0.49) | PTPN1CDC25BELANETDP1 | |
| SCHEMBL9641783 | 0.80 | ELANE (0.46) | PTPN1CDC25BELANETDP1 | |
| SCHEMBL9444193 | 0.80 | CDC25B (0.57) | PTPN1CDC25BPTPRCGAPDHIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |