Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713582 | 0.88 | CDC25B (0.41) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL9713391 | 0.87 | ELANE (0.41) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL9713615 | 0.86 | PTPN1 (0.43) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL9713486 | 0.85 | PTPN1 (0.42) | CDC25BPTPRCPTPN1 | |
| SCHEMBL9714020 | 0.84 | GAPDH (0.38) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL30002572 | 0.83 | IDO1 (0.59) | CDC25BGAPDHCDC25AIDO1ALDH1A1 | |
| SCHEMBL9628632 | 0.83 | IDO1 (0.59) | CDC25BGAPDHCDC25AIDO1ALDH1A1 | |
| SCHEMBL28337556 | 0.82 | GAPDH (0.61) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL9713507 | 0.81 | PTPN1 (0.41) | CDC25BPTPRCGAPDHCDC25AIDO1 | |
| SCHEMBL9642606 | 0.81 | L3MBTL1 (0.43) | CDC25BPTPRCALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |