Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709899 | 0.96 | CNR1 (0.45) | KDM4EMEN1RECQLKMT2ACNR1 | |
| SCHEMBL10707100 | 0.91 | CNR1 (0.45) | KDM4EMEN1RECQLKMT2ACNR1 | |
| SCHEMBL10708295 | 0.89 | CNR1 (0.44) | KDM4EMEN1RECQLKMT2ACNR1 | |
| SCHEMBL9627415 | 0.88 | TOP2A (0.49) | KDM4EMEN1RECQLKMT2ACNR2 | |
| SCHEMBL9627650 | 0.85 | ALOX15 (0.43) | KDM4EMEN1RECQLKMT2ACNR2 | |
| SCHEMBL9627754 | 0.84 | TOP2A (0.48) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL23271696 | 0.84 | KMT2A (0.52) | KDM4EMEN1RECQLKMT2AAKR1C3 | |
| SCHEMBL9713960 | 0.84 | CNR1 (0.44) | KDM4EMEN1KMT2ACNR1CNR2 | |
| SCHEMBL30003035 | 0.84 | KMT2A (0.52) | KDM4EMEN1RECQLKMT2AAKR1C3 | |
| SCHEMBL23271935 | 0.84 | HTT (0.58) | KDM4EMEN1RECQLKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |