Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627415 | 0.92 | TOP2A (0.49) | ALOX15HTTSLC2A1KDM4EMEN1 | |
| SCHEMBL10708295 | 0.90 | CNR1 (0.44) | ALOX15HTTAKR1C3SLC2A1KDM4E | |
| SCHEMBL9628333 | 0.90 | HTT (0.43) | ALOX15HTTSLC2A1KDM4EKMT2A | |
| SCHEMBL10709899 | 0.89 | CNR1 (0.45) | ALOX15HTTAKR1C3SLC2A1KDM4E | |
| SCHEMBL9627867 | 0.87 | MAPT (0.44) | ALOX15HTTAKR1C3SLC2A1KDM4E | |
| SCHEMBL9627564 | 0.87 | ALOX15 (0.43) | ALOX15HTTAKR1C3KDM4EMEN1 | |
| SCHEMBL9628672 | 0.86 | CASP3 (0.46) | ALOX15AKR1C3SLC2A1KDM4EMEN1 | |
| SCHEMBL9627605 | 0.85 | SLC2A1 (0.44) | HTTSLC2A1KDM4ETSHRGLA | |
| SCHEMBL9713564 | 0.85 | KDM4E (0.50) | ALOX15HTTAKR1C3SLC2A1KDM4E | |
| SCHEMBL9627455 | 0.84 | SLC2A1 (0.47) | ALOX15HTTAKR1C3SLC2A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |