Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713918 | 0.99 | CNR1 (0.41) | CNR1CNR2CYP2C9ATMPPARG | |
| SCHEMBL10707692 | 0.87 | THRA (0.39) | CNR1CNR2CYP2C9PPARGPPARA | |
| SCHEMBL9714040 | 0.86 | HTT (0.37) | HTTCYP3A4KDM4EALOX12TDP1 | |
| SCHEMBL10705545 | 0.85 | PPARG (0.43) | CNR1CNR2PPARGPPARATHRA | |
| SCHEMBL9714046 | 0.84 | KDM4E (0.34) | ATMPPARGPPARAHTTPTGS2 | |
| SCHEMBL9642345 | 0.83 | CNR1 (0.38) | CNR1CNR2CYP2C9PPARGPPARA | |
| SCHEMBL9627747 | 0.83 | HTT (0.57) | CNR1CNR2CYP2C9HTTPTGS2 | |
| SCHEMBL9627400 | 0.82 | HTT (0.56) | CNR1CNR2CYP2C9PPARGPPARA | |
| SCHEMBL9628087 | 0.82 | HTT (0.56) | CNR1CNR2CYP2C9PPARGPPARA | |
| SCHEMBL9629327 | 0.81 | HTT (0.44) | HTTCYP3A4KDM4EALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |