Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713618 | 0.86 | CNR1 (0.40) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9713918 | 0.85 | CNR1 (0.41) | CYP3A4MAPTKMT2ALMNA | |
| SCHEMBL9641988 | 0.84 | KDM4E (0.34) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9642578 | 0.81 | NFKB1 (0.33) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9714046 | 0.80 | KDM4E (0.34) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9713619 | 0.80 | HTT (0.37) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9629327 | 0.80 | HTT (0.44) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9641991 | 0.79 | HTT (0.34) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9642520 | 0.79 | NFKB1 (0.33) | HTTKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL9643461 | 0.77 | CCNB2 (0.35) | KDM4ETDP1CYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |