Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712744 | 0.90 | ALDH1A1 (0.45) | SMN1; SMN2TSHRTP53RXFP1CYP1A2 | |
| SCHEMBL9713881 | 0.86 | MAPT (0.36) | SMN1; SMN2RXFP1GAACYP1A2CYP2C19 | |
| SCHEMBL9713120 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2TSHRTP53RXFP1CYP1A2 | |
| SCHEMBL9712819 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2TSHRTP53RXFP1CYP1A2 | |
| SCHEMBL9713470 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRTP53KCNK3KCNK9 | |
| SCHEMBL9712910 | 0.77 | MAPT (0.50) | SMN1; SMN2TSHRTP53RXFP1CYP1A2 | |
| SCHEMBL22535182 | 0.76 | MAPK14 (0.43) | SMN1; SMN2MRGPRX1CYP1A2CYP2C19 | |
| SCHEMBL9713377 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRTP53RXFP1GAA | |
| SCHEMBL9713315 | 0.67 | MAPT (0.46) | SMN1; SMN2TSHRTP53RXFP1KCNK3 | |
| SCHEMBL9712960 | 0.67 | MAPK14 (0.54) | SMN1; SMN2TSHRTP53BRAFCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |