Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712823 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRTP53KCNK3KCNK9 | |
| SCHEMBL9713120 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9713624 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRTP53KCNK3KCNK9 | |
| SCHEMBL9712744 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9712819 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9712910 | 0.77 | MAPT (0.50) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9712925 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9713083 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2TSHRTP53ALDH1A1KDM4E | |
| SCHEMBL9713040 | 0.68 | TP53 (0.49) | SMN1; SMN2TSHRTP53KCNK3KCNK9 | |
| SCHEMBL9713296 | 0.68 | TP53 (0.45) | SMN1; SMN2TSHRTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |