Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713930 | 0.89 | KCNMA1 (0.62) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9857044 | 0.88 | NR1H4 (0.59) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9713529 | 0.88 | NR1H4 (0.59) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9856852 | 0.87 | NR1H4 (0.58) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9857323 | 0.87 | NR1H4 (0.58) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9857076 | 0.87 | NR1H4 (0.60) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9713250 | 0.87 | KCNMA1 (0.62) | NR1H4CYSLTR1CYSLTR2HDAC1FFAR1 | |
| SCHEMBL9713671 | 0.86 | NR1H4 (0.64) | NR1H4CYSLTR1CYSLTR2FFAR1NPC1 | |
| SCHEMBL6581838 | 0.86 | NR1H4 (0.68) | NR1H4CYSLTR1NPC1RAB9AMEN1 | |
| SCHEMBL9713063 | 0.85 | KCNMA1 (0.53) | NR1H4HDAC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |