Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.39 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138128 | 0.83 | EPHX2 (0.50) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL9629440 | 0.82 | KDM4E (0.48) | KMT2AKDM4EMEN1CNR2SMN1; SMN2 | |
| SCHEMBL20398671 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL30003164 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL29372133 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL23271733 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL20398624 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL20398590 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL29368355 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM | |
| SCHEMBL29360726 | 0.81 | EPHX2 (0.51) | DGKAEPHX2CES2CES1POLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |