Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.37 |
| ▸ | TUBB | P07437 | 3/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642160 | 0.83 | ABCB11 (0.70) | ABCB11MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL9627599 | 0.83 | HTT (0.44) | FGFR1MAPTLMNAPDK1ALDH1A1 | |
| SCHEMBL9629306 | 0.82 | ABCB11 (0.68) | ABCB11MAPTLMNAALDH1A1TUBB4A | |
| SCHEMBL9659152 | 0.82 | ABCB11 (0.52) | ABCB11MAPTLMNAALDH1A1TUBB4A | |
| SCHEMBL9656665 | 0.82 | ABCB11 (0.47) | ABCB11MAPTLMNAALDH1A1TUBB4A | |
| SCHEMBL9713949 | 0.81 | ABCB11 (0.49) | ABCB11FGFR1MAPTLMNAALDH1A1 | |
| SCHEMBL9657963 | 0.81 | ABCB11 (0.55) | ABCB11MAPTLMNAALDH1A1TUBB4A | |
| SCHEMBL9656392 | 0.81 | ABCB11 (0.49) | ABCB11MAPTALDH1A1TUBB4ATUBB | |
| SCHEMBL9628189 | 0.80 | ABCB11 (0.70) | ABCB11MAPTLMNAALDH1A1TUBB4A | |
| SCHEMBL9627379 | 0.79 | ABCB11 (0.68) | ABCB11MAPTLMNAALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |