Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658050 | 0.84 | ABCB11 (0.69) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9658069 | 0.84 | NCEH1 (0.51) | KMT2AMEN1ALDH1A1NCEH1LPAR1 | |
| SCHEMBL9660007 | 0.82 | ABCB11 (0.50) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9629306 | 0.81 | ABCB11 (0.68) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9659152 | 0.81 | ABCB11 (0.52) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9713742 | 0.81 | ABCB11 (0.49) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9659003 | 0.81 | ABCB11 (0.52) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10643955 | 0.81 | ABCB11 (0.44) | ABCB11ALDH1A1 | |
| SCHEMBL9657710 | 0.81 | ATM (0.57) | ABCB11KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9657963 | 0.80 | ABCB11 (0.55) | ABCB11KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |