Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714211 | 0.84 | ALDH1A1 (0.41) | NPSR1GAAMAPK1POLBSMN1; SMN2 | |
| SCHEMBL9713926 | 0.83 | ALDH1A1 (0.50) | GAAALDH1A1LMNACYP3A4HPGD | |
| SCHEMBL13215154 | 0.77 | MAPK1 (0.56) | NPSR1GAAMAPK1POLBSMN1; SMN2 | |
| SCHEMBL13215132 | 0.76 | MAPK1 (0.52) | NPSR1GAAMAPK1ALDH1A1CASP3 | |
| SCHEMBL31384765 | 0.76 | MAPK1 (0.52) | NPSR1GAAMAPK1ALDH1A1CASP3 | |
| SCHEMBL3533533 | 0.76 | ALDH1A1 (0.65) | GAAMAPK1ALDH1A1CYP1A2MAPT | |
| SCHEMBL2839402 | 0.76 | ALDH1A1 (0.58) | GAAMAPK1ALDH1A1CASP3CASP7 | |
| SCHEMBL4861445 | 0.76 | MAPK1 (0.57) | NPSR1GAAMAPK1POLBSMN1; SMN2 | |
| SCHEMBL4861358 | 0.73 | MAPK1 (0.55) | NPSR1GAAMAPK1POLBALDH1A1 | |
| SCHEMBL3531540 | 0.73 | ALDH1A1 (0.56) | NPSR1GAAMAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |