Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713926 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTR6HSD11B1LMNAMPO | |
| SCHEMBL9713841 | 0.84 | NPSR1 (0.56) | ALDH1A1SMN1; SMN2NPSR1MAPK1LMNA | |
| SCHEMBL7777372 | 0.72 | MEN1 (0.51) | ALDH1A1SMN1; SMN2NPSR1MEN1MAPK1 | |
| SCHEMBL15651103 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2NPSR1MEN1MAPK1 | |
| SCHEMBL8320409 | 0.71 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2MAPK1TSHRPOLB | |
| SCHEMBL21305523 | 0.70 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2NPSR1MEN1MAPK1 | |
| SCHEMBL9713990 | 0.68 | HTR6 (0.50) | ALDH1A1MEN1KMT2AHTR6HSD11B1 | |
| SCHEMBL3928072 | 0.68 | CYP19A1 (0.55) | ALDH1A1SMN1; SMN2HTR6PKMKDM4E | |
| SCHEMBL9713812 | 0.67 | PKM (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AHTR6 | |
| SCHEMBL157598 | 0.67 | HSD17B10 (0.59) | ALDH1A1SMN1; SMN2MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |