Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | CDC25B | P30305 | 4/20 | 0.69 |
| ▸ | CDC25A | P30304 | 3/20 | 0.69 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420371 | 0.90 | CDC25B (0.60) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL29545010 | 0.83 | MAPT (1.00) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL571557 | 0.83 | MAPT (1.00) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9627838 | 0.80 | CDC25B (0.61) | MAPTALDH1A1KDM4EPOLBLMNA | |
| Benzene SCHEMBL9714013 | 0.79 | NSD2 (0.58) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9627536 | 0.78 | CDC25B (0.53) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9628254 | 0.78 | MAPT (0.65) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9641989 | 0.78 | CDC25B (0.52) | MAPTALDH1A1KDM4EPOLBLMNA | |
| Benzene SCHEMBL9642799 | 0.78 | TTR (0.56) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL10446464 | 0.77 | IDO1 (0.56) | MAPTALDH1A1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |