Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627484 | 0.91 | HTT (0.51) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9713348 | 0.87 | HTT (0.48) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9628275 | 0.87 | HTT (0.48) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9713846 | 0.85 | HTT (0.46) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL14599183 | 0.80 | HTT (0.46) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL3293017 | 0.78 | POLB (0.51) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL7918996 | 0.78 | HTT (0.75) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9627440 | 0.77 | TNFSF11 (0.50) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9641857 | 0.77 | ABCB11 (0.62) | HTTPOLBKDM4EGAAMAPT | |
| SCHEMBL9627649 | 0.76 | HTT (0.50) | HTTPOLBKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |