Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.49 |
| ▸ | MMP2 | P08253 | 9/20 | 0.49 |
| ▸ | MMP3 | P08254 | 7/20 | 0.49 |
| ▸ | MMP8 | P22894 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 5/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 10/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MMP20 | O60882 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP15 | P51511 | 1/20 | 0.39 |
| ▸ | MMP16 | P51512 | 1/20 | 0.39 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.39 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MMP24 | Q9Y5R2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714087 | 0.84 | MMP1 (0.41) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL6435813 | 0.75 | MMP2 (0.48) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL8872304 | 0.70 | MMP1 (0.51) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL8872299 | 0.70 | MMP1 (0.51) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL9714184 | 0.70 | DPP4 (0.40) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL9714104 | 0.66 | DPP4 (0.36) | DPP4 | |
| SCHEMBL9714151 | 0.66 | MMP1 (1.00) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL10002508 | 0.65 | DPP4 (0.50) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL20472978 | 0.65 | DPP4 (0.50) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL21086856 | 0.63 | DPP4 (0.58) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |