Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924523 | 0.87 | CYP3A4 (0.47) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9713985 | 0.87 | CYP3A4 (0.48) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9714166 | 0.85 | HSP90AA1 (0.41) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9279962 | 0.82 | KMT2A (0.51) | HSP90AA1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL9714174 | 0.80 | HSP90AA1 (0.37) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9736623 | 0.79 | HSP90AA1 (0.40) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9735760 | 0.79 | HSP90AA1 (0.40) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9735763 | 0.79 | HSP90AA1 (0.40) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL9714186 | 0.79 | CYP3A4 (0.64) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 | |
| SCHEMBL29058727 | 0.79 | CYP3A4 (0.54) | HSP90AA1CYP3A4CYP2C9CYP2C19CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017474-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |