Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714479 | 0.91 | ABCB1 (0.55) | POLBABCB1ALDH1A1 | |
| SCHEMBL9714633 | 0.91 | ALDH1A1 (0.56) | ABCB1ALDH1A1CTSD | |
| SCHEMBL10722623 | 0.90 | POLB (0.58) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714639 | 0.90 | POLB (0.63) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9825684 | 0.88 | SMN1; SMN2 (0.64) | POLBCYP3A4ABCB1ALDH1A1CTSD | |
| SCHEMBL9714285 | 0.87 | ABCB1 (0.58) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714095 | 0.87 | POLB (0.56) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10722858 | 0.86 | POLB (0.55) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714336 | 0.85 | SMN1; SMN2 (0.48) | POLBABCB1ALDH1A1CTSD | |
| SCHEMBL9714396 | 0.85 | ABCB1 (0.56) | CYP3A4CYP2C9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |