SCHEMBL9714387

SCHEMBL9714387

COc1ccccc1C(=O)N(NC(=O)c1ccccc1)C(C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.67
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9714501 0.90 ABCB1 (0.60)
SCHEMBL9714386 0.89 POLB (0.67) POLBCYP3A4CYP2C9
SCHEMBL9714050 0.87 POLB (0.63) POLBCYP3A4CYP2C9
SCHEMBL9714499 0.86 ABCB1 (0.57) POLBCYP3A4CYP2C9
SCHEMBL9755913 0.85 ABCB1 (0.51)
SCHEMBL10720173 0.84 ABCB1 (0.64)
SCHEMBL9755979 0.84 ABCB1 (0.52)
SCHEMBL9756344 0.84 ABCB1 (0.51)
SCHEMBL8383736 0.82 ABCB1 (0.79) POLBCYP3A4CYP2C9
SCHEMBL10722300 0.82 ABCB1 (0.61) POLBCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US claimed
EP-0245950-B1 INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-06-17 EP disclosed
EP-0236618-B1 INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US disclosed
EP-0236618-A2 Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-16 EP disclosed