SCHEMBL9755979

SCHEMBL9755979

COc1ccccc1C(=O)N(NC(=O)C1=CC1)C(C)(C)C

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.52
CTSD P07339 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756151 0.90 ABCB1 (0.50) ABCB1
SCHEMBL9755982 0.90 ABCB1 (0.55) ABCB1CTSD
SCHEMBL9714501 0.88 ABCB1 (0.60) ABCB1CTSD
SCHEMBL9756258 0.86 ABCB1 (0.47) ABCB1
SCHEMBL9756345 0.85 ABCB1 (0.46) ABCB1
SCHEMBL9756144 0.85 ABCB1 (0.46) ABCB1
SCHEMBL9756140 0.85 ABCB1 (0.46) ABCB1
SCHEMBL9714387 0.84 POLB (0.67)
SCHEMBL9756154 0.82 ABCB1 (0.53) ABCB1CTSD
SCHEMBL9755913 0.82 ABCB1 (0.51) ABCB1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP disclosed
EP-0232075-B1 INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-03-13 EP disclosed
EP-0232075-A1 Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines ROHM AND HAAS COMPANY (US) 1987-08-12 EP disclosed
EP-0213082-A1 Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals SANDOZ AG (CH) 1987-03-04 EP disclosed