SCHEMBL9755913

SCHEMBL9755913

COc1ccccc1C(=O)N(NC(C)=O)C(C)(C)C

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.51
CTSD P07339 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9714501 0.88 ABCB1 (0.60) ABCB1CTSD
SCHEMBL9714387 0.85 POLB (0.67)
SCHEMBL9756344 0.85 ABCB1 (0.51) ABCB1
SCHEMBL9756387 0.83 ABCB1 (0.47) ABCB1
SCHEMBL9756059 0.83 ABCB1 (0.47) ABCB1
SCHEMBL9755862 0.82 ABCB1 (0.46) ABCB1
SCHEMBL9755979 0.82 ABCB1 (0.52) ABCB1CTSD
SCHEMBL9756274 0.82 ABCB1 (0.46) ABCB1
SCHEMBL9756389 0.82 ABCB1 (0.46) ABCB1
SCHEMBL10720173 0.82 ABCB1 (0.64) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP disclosed
EP-0232075-B1 INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-03-13 EP disclosed
EP-0232075-A1 Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines ROHM AND HAAS COMPANY (US) 1987-08-12 EP disclosed