SCHEMBL97145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2088259	0.83	ALDH1A1 (0.64)	MAPTALDH1A1HTTKDM4ENAMPT
	SCHEMBL95558	0.82	NPC1 (0.76)	MAPTALDH1A1NAMPTPOLBTP53
	SCHEMBL95606	0.81	MAPT (0.56)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL95125	0.78	NAMPT (0.61)	MAPTALDH1A1HTTNAMPTTP53
	SCHEMBL95269	0.78	SMN1; SMN2 (0.67)	MAPTALDH1A1HTTKDM4ETP53
	SCHEMBL5658638	0.78	KMT2A (0.53)	MAPTALDH1A1HTTKDM4ETP53
	SCHEMBL94356	0.78	CACNA1B (0.71)	MAPTALDH1A1HTTPOLBTP53
	SCHEMBL96146	0.77	MLYCD (0.68)	MAPTALDH1A1GAAMEN1KMT2A
	SCHEMBL3702677	0.77	NAMPT (1.00)	MAPTALDH1A1HTTKDM4ENAMPT
	SCHEMBL6354556	0.77	ALDH1A1 (0.59)	MAPTALDH1A1HTTKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.