Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590859 | 0.90 | TDP1 (0.46) | TDP1ATMCETPALDH1A1HIF1A | |
| SCHEMBL10589912 | 0.90 | TDP1 (0.46) | TDP1ATMCETPALDH1A1HIF1A | |
| SCHEMBL10590180 | 0.88 | TDP1 (0.47) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL10591334 | 0.88 | TDP1 (0.47) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL10590571 | 0.87 | ATM (0.44) | TDP1ATMCETPALDH1A1HIF1A | |
| SCHEMBL30532293 | 0.85 | ATM (0.55) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL969906 | 0.85 | ATM (0.55) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL10590498 | 0.85 | ATM (0.42) | TDP1ATMCETPALDH1A1HIF1A | |
| SCHEMBL10590577 | 0.83 | ATM (0.40) | TDP1ATMCETPALDH1A1HIF1A | |
| SCHEMBL692339 | 0.82 | ATM (0.55) | TDP1ATMALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157155-A | Insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-20 | — | — | US | disclosed |
| EP-0277748-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-4985460-A | Ovicide and Chemosterilant for Insects | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4904696-A | Benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0277748-A1 | A benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |