Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532293 | 1.00 | ATM (0.55) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13581006 | 0.87 | TDP1 (0.49) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31237064 | 0.86 | ALDH1A1 (0.53) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1275648 | 0.86 | ALDH1A1 (0.53) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9714508 | 0.85 | TDP1 (0.50) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10591075 | 0.85 | TDP1 (0.50) | ATMTDP1MEN1KMT2AMAPT | |
| SCHEMBL10591334 | 0.83 | TDP1 (0.47) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10590180 | 0.83 | TDP1 (0.47) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10590571 | 0.82 | ATM (0.44) | ATMTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17786752 | 0.82 | ATM (0.62) | ATMTDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562306-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2025-02-26 | — | — | EP | disclosed |
| EP-4472739-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2024-12-11 | — | — | EP | disclosed |
| US-11919883-B2 | Metalloenzyme inhibitor compounds | JI XING PHARMACEUTICALS HONG KONG LIMITED (HK) | 2024-03-05 | — | — | US | disclosed |
| CN-112955436-B | 6-oxo-1, 6-dihydropyridazine derivatives, preparation method and application thereof in medicines | 福建盛迪医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |
| US-20220073471-A1 | 6-OXO-1,6-DIHYDROPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2022-03-10 | — | — | US | disclosed |
| US-20220009907-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2022-01-13 | — | — | US | disclosed |
| US-11136309-B2 | Metalloenzyme inhibitor compounds | PHASEBIO PHARMACEUTICALS, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| CN-112955436-A | 6-oxo-1, 6-dihydropyridazine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20200392112-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2020-12-17 | — | — | US | disclosed |
| US-7750158-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1768667-B1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-09-30 | — | — | EP | disclosed |
| WO-2009070584-A1 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-A]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 | WYETH (US) | 2009-06-04 | — | — | WO | disclosed |
| US-20090143367-A1 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-a]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 | ELBION GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143367-A1 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-a]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 | ELBION GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| CN-101005838-A | Cannabinoid receptor ligands | SCHERING CORP (US) | 2007-07-25 | — | — | CN | disclosed |
| EP-1768667-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2007-04-04 | — | — | EP | disclosed |
| US-20060100228-A1 | Cannabinoid receptor ligands | SCHERING CORPORATION | 2006-05-11 | — | — | US | disclosed |
| WO-2006002133-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2006-01-05 | — | — | WO | disclosed |
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100228-A1 | Cannabinoid receptor ligands | CNR1, CNR2, TRPV1 | ATM 3649/4885TDP1 4103/4885MEN1 3202/4885 |
| US-20220073471-A1 | 6-OXO-1,6-DIHYDROPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | CACNA1D, CACNA1F, CACNA1B | ATM 4293/4885TDP1 1474/4885MEN1 2422/4885 |
| US-20200392112-A1 | METALLOENZYME INHIBITOR COMPOUNDS | SOD1, RNASE1, FECH | ATM 3366/4885TDP1 1270/4885MEN1 720/4885 |
| US-20220009907-A1 | METALLOENZYME INHIBITOR COMPOUNDS | SOD1, RNASE1, FECH | ATM 3366/4885TDP1 1270/4885MEN1 720/4885 |
| US-20090143367-A1 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-a]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 | PDE12, PDE5A, PDE10A | ATM 3412/4885TDP1 39/4885MEN1 2827/4885 |
| US-11136309-B2 | Metalloenzyme inhibitor compounds | SOD1, RNASE1, FECH | ATM 3366/4885TDP1 1270/4885MEN1 720/4885 |
| US-11919883-B2 | Metalloenzyme inhibitor compounds | SOD1, RNASE1, FECH | ATM 3366/4885TDP1 1270/4885MEN1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.