Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714631 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL9714638 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL9276381 | 0.87 | ALDH1A1 (0.62) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL9276383 | 0.87 | ALDH1A1 (0.62) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL18821936 | 0.87 | ALDH1A1 (0.41) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL119647 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4RECQLGRIK1GRIK2 | |
| SCHEMBL119646 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4RECQLGRIK1GRIK2 | |
| SCHEMBL3466529 | 0.78 | CYP2C19 (0.43) | ALDH1A1CYP3A4GRIK1GRIK2IDO1 | |
| SCHEMBL3466530 | 0.78 | CYP2C19 (0.43) | ALDH1A1CYP3A4GRIK1GRIK2IDO1 | |
| SCHEMBL221968 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP3A4RECQLAPPPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262404-B1 | GLUCOSYLMORANOLINE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4855415-A | Glucosylmoranoline derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0262404-A1 | Glucosylmoranoline derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |