SCHEMBL119647

SCHEMBL119647

OCC=Cc1ccc(Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 2/20 0.52
RECQL P46063 2/20 0.52
GRIK1 P39086 1/20 0.45
GRIK2 Q13002 1/20 0.45
CYP2C19 P33261 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
MAPT P10636 3/20 0.41
CYP2D6 P10635 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2C9 P11712 1/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119646 1.00 ALDH1A1 (0.52) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL9276381 0.87 ALDH1A1 (0.62) ALDH1A1CYP3A4RECQLCYP2C19KDM4E
SCHEMBL9276383 0.87 ALDH1A1 (0.62) ALDH1A1CYP3A4RECQLCYP2C19KDM4E
SCHEMBL29278706 0.82 CYP2C19 (0.44) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL9714631 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL9714628 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL9714638 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL29278715 0.79 GRIK1 (0.41) ALDH1A1CYP3A4RECQLGRIK1GRIK2
SCHEMBL221967 0.78 ALDH1A1 (0.59) ALDH1A1CYP3A4RECQLCYP2C19KDM4E
SCHEMBL3466530 0.78 CYP2C19 (0.43) ALDH1A1CYP3A4GRIK1GRIK2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-116553858-B Low-carbon concrete additive and preparation method and application thereof 湖南凝英新材料科技有限公司 2023-09-05 CN claimed
CN-116553858-A Low-carbon concrete additive and preparation method and application thereof 湖南凝英新材料科技有限公司 2023-08-08 CN claimed
CN-115716776-A Method for synthesizing alcohol compound by catalyzing alpha, beta-unsaturated aldehyde 化学与精细化工广东省实验室 2023-02-28 CN claimed
CN-113277963-B Amine compound and preparation method and application thereof 南京工业大学 2022-11-04 CN claimed
CN-114854222-A Aging-resistant asphalt for muck lane and preparation method thereof 刘敏泉 2022-08-05 CN claimed
CN-113277963-A Amine compound and preparation method and application thereof 南京工业大学 2021-08-20 CN claimed
CN-108947754-B Use of bidentate phosphite ligands in C-F bond building reactions 郑州大学 2021-02-26 CN claimed
CN-108993600-B Use of bidentate phosphite ligands in C-B bond building reactions 郑州大学 2021-01-22 CN claimed
US-10112896-B2 Method for synthesizing dissymmetric sulfoether SOOCHOW UNIVERSITY (CN) 2018-10-30 US claimed
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER SOOCHOW UNIVERSITY (CN) 2018-07-19 US claimed
CN-102337307-A Preparation method of optically active phenyl glycidol and derivatives thereof CHENGDU INST BIOLOGY CAS 2012-02-01 CN claimed
US-20260132144-A1 METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-05-14 US disclosed
EP-4719605-A1 CHEMICAL COMPOUNDS AND USES THEREOF GlaxoSmithKline Intellectual Property (No.4) Limited (GB) 2026-04-08 EP disclosed
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) 2026-01-15 US disclosed
US-20250051299-A1 PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE DAIKIN INDUSTRIES, LTD. (JP) 2025-02-13 US disclosed
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10112896-B2 Method for synthesizing dissymmetric sulfoether STS, TST, SCLY ALDH1A1 842/4885CYP3A4 580/4885RECQL 3063/4885
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER STS, TST, SCLY ALDH1A1 842/4885CYP3A4 580/4885RECQL 3063/4885
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF WRN, MSH2, MSH6 ALDH1A1 1151/4885CYP3A4 3820/4885RECQL 6/4885
US-20260132144-A1 METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS CYP2C9, ODC1, AOC2 ALDH1A1 770/4885CYP3A4 85/4885RECQL 1284/4885
US-20250051299-A1 PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE AFF1, AFF2, ROS1 ALDH1A1 111/4885CYP3A4 79/4885RECQL 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.